Gerasimenko Iu P, Lavrov I A, Bogacheva I N, Shcherbakova N A, Kucher V I, Musienko P E
I. P. Pavlov Institute of Physiology, Russian Acad. Sci., 199034, St. Petersburg, Nab. Makarova, 6, Russia.
Ross Fiziol Zh Im I M Sechenova. 2003 Sep;89(9):1046-57.
The mechanisms of stepping pattern formation initiated by epidural spinal cord stimulation in decerebrated cats, were investigated. It is shown that the ability to produce the stepping pattern involve the L3-L5 segments. In flexor muscle, the formation of stepping pattern under optimal stimulation frequency (5-10 Hz) of these segments is provided by polysynaptic activity with the latency 80-110 ms. In extensor muscle, this process is realized through interaction of monosynaptic reflex and polysynaptic activity. The stepping pattern under epidural stimulation is determined by spinal structures with modulation influence of the peripheral feedback.
研究了去大脑猫中硬膜外脊髓刺激引发的步态模式形成机制。结果表明,产生步态模式的能力涉及L3 - L5节段。在屈肌中,在这些节段的最佳刺激频率(5 - 10赫兹)下,步态模式的形成由潜伏期为80 - 110毫秒的多突触活动提供。在伸肌中,这个过程通过单突触反射和多突触活动的相互作用来实现。硬膜外刺激下的步态模式由脊髓结构决定,并受外周反馈的调节影响。