Davies T G, Renton C P
Vet Rec. 1992 Dec 5;131(23):528-31.
Two outbreaks of Salmonella typhimurium infections affected outwintered, spring-calving suckler cows in late pregnancy. The infections spread rapidly both within and between groups of stock on the affected farms, with morbidity in the infected groups varying from 14.5 per cent to over 60 per cent, and mortality in adult cattle varying from 0 to 14.3 per cent. Prophylactic measures included the use of antibiotics and killed vaccines against Escherichia coli, Salmonella dublin, S typhimurium, and Pasteurella multocida. In one outbreak, use was also made of a polyvalent serovaccine and hyperimmune serum against E coli, S typhimurium, and S dublin. In both outbreaks no new cases were reported in the affected groups after the administration of the second dose of vaccine, and there was no resurgence of disease on the affected farms within 18 months of the primary outbreaks.
两起鼠伤寒沙门氏菌感染疫情影响了越冬的、春季产犊的妊娠后期哺乳母牛。感染在受影响农场的畜群内部和不同畜群之间迅速传播,感染群体的发病率从14.5%到超过60%不等,成年牛的死亡率从0到14.3%不等。预防措施包括使用抗生素以及针对大肠杆菌、都柏林沙门氏菌、鼠伤寒沙门氏菌和多杀性巴氏杆菌的灭活疫苗。在一次疫情中,还使用了针对大肠杆菌、鼠伤寒沙门氏菌和都柏林沙门氏菌的多价血清疫苗和高免血清。在两次疫情中,在接种第二剂疫苗后,受影响群体均未报告新病例,并且在初次疫情后的18个月内,受影响农场未出现疾病复发情况。