Schultz Larsen F, Hanifin J M
Skin Clinic, Fredericia, Denmark.
Acta Derm Venereol Suppl (Stockh). 1992;176:7-12.
Atopic dermatitis is a common disease, and population-based studies indicate that the frequency of atopic dermatitis has increased substantially during recent decades. It has been generally accepted that disease onset occurs before 7 years of age in 80-90% of the cases, and consequently the epidemiology of atopic dermatitis has been studied mostly in children on admission of first grade school. Before 1960 about 2-3% of children suffered from atopic dermatitis. In the 1960s, some 4-8% was recorded in several studies, and for those born after 1970 most researchers found that 9-12% developed atopic dermatitis during childhood. The diagnostic criteria of Hanifin and Rajka are cumbersome for population studies not designed specifically for children. In order to compare epidemiologic data from varying times and locations, a framework for questionnaire studies in atopic dermatitis is proposed.
特应性皮炎是一种常见疾病，基于人群的研究表明，近几十年来特应性皮炎的发病率大幅上升。人们普遍认为，80%-90%的病例在7岁之前发病，因此特应性皮炎的流行病学主要是在小学一年级入学儿童中进行研究的。1960年以前，约2%-3%的儿童患有特应性皮炎。在20世纪60年代，几项研究记录的发病率约为4%-8%，对于1970年以后出生的人，大多数研究人员发现9%-12%的人在儿童期患特应性皮炎。Hanifin和Rajka的诊断标准对于并非专门针对儿童设计的人群研究来说很繁琐。为了比较不同时间和地点的流行病学数据，本文提出了一个特应性皮炎问卷调查研究的框架。
