Cheng C T
Department of Forensic Medicine, Singapore.
Am J Forensic Med Pathol. 1992 Sep;13(3):261-3. doi: 10.1097/00000433-199209000-00020.
In October 1988, a series of food poisoning cases occurred in the State of Perak in Malaysia. Most of the victims were children. Ultimately 13 children between the ages of 2.5 and 11 years died. Epidemiological investigations showed that the probable source of the poison was Loh See Fun, a noodles in the shape of a rat's tail. All the deceased ate the noodles from one supplier. Clinical and pathological findings were similar in each case. Postmortem examination was performed in 11 cases. Toxicological examination on organs in 10 cases showed a high concentration of aflatoxin in tissues of the deceased. High levels of boric acid were excreted from most of the victims. Histological examination of the liver in these cases showed necrotic changes found in aflatoxin poisoning. Combination of the epidemiological, clinical, toxicological, and pathological findings pointed to the fact that there was a common toxin or toxins responsible for the deaths. These were thought to be a combination of boric acid and aflatoxin.
1988年10月，马来西亚霹雳州发生了一系列食物中毒事件。大多数受害者是儿童。最终，13名年龄在2.5岁至11岁之间的儿童死亡。流行病学调查显示，中毒的可能源头是老鼠尾巴形状的面条——老鼠粉。所有死者都食用了来自同一供应商的面条。每例病例的临床和病理表现相似。11例进行了尸检。对10例死者器官的毒理学检查显示，死者组织中黄曲霉毒素浓度很高。大多数受害者体内排出了高含量的硼酸。这些病例肝脏的组织学检查显示出黄曲霉毒素中毒时出现的坏死变化。流行病学、临床、毒理学和病理学调查结果综合起来表明，存在一种或多种导致死亡的共同毒素。据认为，这些毒素是硼酸和黄曲霉毒素的混合物。
