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椭圆叶山香圆对皮肤真菌的抗菌活性。

Antimicrobial activity of Hyptis ovalifolia towards dermatophytes.

作者信息

Souza Lúcia K H, de Oliveira Cecília M A, Ferri Pedro H, de Oliveira Júnior Juldásio Galdino, de Souza Júnior Ary Henrique, Fernandes Orionalda de Fátima Lisboa, Silva Maria do Rosário R

机构信息

Laboratório de Micologia, Instituto de Patologia Tropical e Saúde Pública, Universidade Federal de Goiás, Goiânia, GO, Brasil.

出版信息

Mem Inst Oswaldo Cruz. 2003 Oct;98(7):963-5. doi: 10.1590/s0074-02762003000700018. Epub 2004 Jan 7.

Abstract

The essential oil and the aqueous, hexane and methanolic fractions from Hyptis ovalifolia leaves were evaluated for their antifungal activity in vitro against 60 strains of dermatophytes: 10 strains of Microsporum canis, 10 of M. gypseum, 20 of Trichophyton rubrum and 20 of T. mentagrophytes. The extracts inhibited growth of the dermatophytes tested at different concentrations. The most biologically active was the essential oil from the leaves which inhibited 57 isolates (95%) at a concentration of 500 g/ml.

摘要

对椭圆叶香科叶草叶片的精油以及水相、己烷相和甲醇相提取物进行了体外抗真菌活性评估,受试对象为60株皮肤癣菌:10株犬小孢子菌、10株石膏样小孢子菌、20株红色毛癣菌和20株须癣毛癣菌。提取物在不同浓度下均能抑制受试皮肤癣菌的生长。其中生物活性最强的是叶片精油,在浓度为500微克/毫升时可抑制57株分离菌(95%)。

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