Burić Nikola, Jovanović Goran, Krasić Dragan, Kesić Ljiljana
Department of Oral and Maxillofacial Surgery, Clinic of Stomatology, Faculty of Medicine in Nis, Serbia.
J Oral Sci. 2003 Dec;45(4):207-12.
This paper reports the results of experimental use of glass-ionomer microimplants in the augmentation of the maxillary alveolar ridge in dogs. The study included ten adult mongrel dogs 5 years of age, weighing between 50 and 70 pounds (25-30 kg), divided into 2 groups of 5 dogs each. In both groups, the maxillary 4th premolar and 1st molar were removed after the elevation of a buccal mucoperiosteal flap. The alveolar bone adjacent to the extracted teeth was also removed. In the experimental group (5 dogs), Ionogran a glass-ionomer microimplants (GIMIs) (Ionogran particle size of 0.5-1.0 mm, IONOS Medizinische Produkte GmbH & Co. KG, D-8031 Seefeld, Gemany) were used for augmentation and were inserted in the created defects. The extraction sockets and bone defects were augmented with an average amount of 2 g of GIMIs. In the control group, the bone defects were left unfilled as a control for bone healing. Histological examination showed that the glass-ionomer microimplants were extremely osteoconductive and inert materials. Stimulation of growth of new bone tissue in contact with the glass-ionomer microimplants was evident. No inflammatory cells were detected on or adjacent to the GIMIs. In the control group, incomplete bone healing with fibrous scar tissue and inflammatory cells was noted. These results indicate that glass-ionomer microimplants represent highly osteoconductive and biocompatible materials for use in bone surgery.
本文报道了玻璃离子微种植体在犬上颌牙槽嵴增高术中的实验应用结果。该研究纳入了10只5岁的成年杂种犬，体重在50至70磅（25 - 30千克）之间，分为两组，每组5只。两组均在掀起颊侧黏骨膜瓣后拔除上颌第四前磨牙和第一磨牙，并去除拔除牙齿相邻的牙槽骨。在实验组（5只犬）中，使用Ionogran玻璃离子微种植体（GIMIs）（Ionogran颗粒大小为0.5 - 1.0毫米，IONOS Medizinische Produkte GmbH & Co. KG，德国塞费尔德8031）进行增高术，并将其植入所形成的缺损处。拔牙窝和骨缺损平均用2克GIMIs进行填充。在对照组中，骨缺损未进行填充，作为骨愈合的对照。组织学检查显示，玻璃离子微种植体是极具骨传导性的惰性材料。与玻璃离子微种植体接触的新骨组织生长明显受到刺激。在GIMIs上或其附近未检测到炎性细胞。在对照组中，观察到骨愈合不完全，伴有纤维瘢痕组织和炎性细胞。这些结果表明，玻璃离子微种植体是用于骨外科手术的极具骨传导性和生物相容性的材料。
