阿司匹林和非甾体抗炎药引起呼吸道反应患者的治疗

Treatment of patients with respiratory reactions to aspirin and nonsteroidal anti-inflammatory drugs.

作者信息

Simon Ronald A

机构信息

Division of Allergy, Asthma and Immunology, Scripps Clinic, 10666 North Torrey Pines Road, 205W, La Jolla, CA 92037, USA.

出版信息

Curr Allergy Asthma Rep. 2004 Mar;4(2):139-43. doi: 10.1007/s11882-004-0059-4.

DOI:10.1007/s11882-004-0059-4

PMID:14769263

Abstract

Aspirin exacerbated respiratory disease (AERD) is an adult onset condition manifested as asthma, rhinosinusitis/nasal polyps, and sensitivity to aspirin and other cyclooxygenase-1 (Cox-1)-inhibitor nonsteroidal anti-inflammatory drugs (NSAIDs). There is no cross-sensitivity to highly selective Cox-2 inhibitors.

摘要

阿司匹林加重性呼吸系统疾病（AERD）是一种成年起病的病症，表现为哮喘、鼻窦炎/鼻息肉，以及对阿司匹林和其他环氧化酶-1（Cox-1）抑制剂非甾体抗炎药（NSAIDs）敏感。对高选择性Cox-2抑制剂不存在交叉敏感性。