Memish Ziad A, Balkhy Hanan H
Department of Infection Prevention and Control and Department of Medicine, King Abdulaziz Medical City, King Fahad National Guard Hospital, Riyadh, Saudi Arabia.
J Travel Med. 2004 Jan-Feb;11(1):49-55. doi: 10.2310/7060.2004.13551.
Brucellosis is a zoonotic disease of worldwide distribution that mainly affects persons working with domestic animals and animal products. Despite being controlled in many developed countries, the disease remains endemic in many parts of the world, including Latin America, the Middle East, Spain, parts of Africa, and western Asia. The disease is mainly transmitted to humans through the ingestion of raw milk or non-pasteurized cheese contaminated with one of the four Brucella species pathogenic to humans. The clinical presentation can vary from asymptomatic infection with seroconversion to a full-blown clinical picture of fever, night sweats and joint manifestations; rarely, there is hepatic, cardiac, ocular or central nervous system involvement. Since travelers may be affected, travel health physicians need to know the clinical presentation of patients with brucellosis and preventive strategies.
布鲁氏菌病是一种分布于全球的人畜共患病，主要影响从事家畜及畜产品工作的人员。尽管在许多发达国家该病已得到控制，但在世界许多地区，包括拉丁美洲、中东、西班牙、部分非洲地区和西亚，该病仍然流行。该病主要通过摄入被四种对人类致病的布鲁氏菌属之一污染的生乳或未杀菌奶酪传播给人类。临床表现从无症状血清学转换感染到发热、盗汗和关节表现的全面临床症状不等；很少有肝脏、心脏、眼部或中枢神经系统受累情况。由于旅行者也可能受到影响，旅行健康医生需要了解布鲁氏菌病患者的临床表现及预防策略。
