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保留乳头的乳房切除术:54例手术的技术与结果

Nipple-sparing mastectomy: technique and results of 54 procedures.

作者信息

Crowe Joseph P, Kim Julian A, Yetman Randall, Banbury Jillian, Patrick Rebecca J, Baynes Deborah

机构信息

Departments of General Surgery and Plastic Surgery, The Cleveland Clinic Breast Center, The Cleveland Clinic Foundation, Cleveland, Ohio, USA.

出版信息

Arch Surg. 2004 Feb;139(2):148-50. doi: 10.1001/archsurg.139.2.148.

Abstract

HYPOTHESIS

The rationale for removal of the nipple-areolar complex (NAC) during total mastectomy centers on long-standing concerns about possible neoplastic involvement of the NAC and its postoperative viability. Nipple-sparing mastectomy (NSM) combines a skin-sparing mastectomy with preservation of the NAC, intraoperative pathological assessment of the nipple tissue core, and immediate reconstruction, thereby permitting better cosmesis for patients undergoing total mastectomy. Neoplastic involvement of the NAC can be predicted before surgery and assessed during the operation, and sustained postoperative viability of the NAC is likely with appropriate surgical technique.

RESULTS

Fifty-four NSMs with immediate reconstruction were attempted among 44 patients. Six NAC core specimens revealed neoplastic involvement on frozen section analysis, resulting in conversion to total mastectomies. Forty-five of the 48 completed NSMs maintained postoperative viability of the NAC; 3 NACs had partial loss.

CONCLUSION

Nipple-sparing mastectomy is a reasonable option for carefully screened patients.

摘要

假设

在全乳切除术中切除乳头乳晕复合体(NAC)的基本原理,长期以来集中在对NAC可能发生肿瘤累及及其术后存活能力的担忧上。保乳手术(NSM)将保留皮肤的乳房切除术与保留NAC、乳头组织核心的术中病理评估以及即刻重建相结合,从而为接受全乳切除术的患者提供更好的美容效果。NAC的肿瘤累及情况可以在手术前预测,并在手术中进行评估,采用适当的手术技术,NAC术后有可能维持存活能力。

结果

在44例患者中尝试了54例NSM并即刻重建。6例NAC核心标本在冰冻切片分析中显示有肿瘤累及,导致转为全乳切除术。48例完成的NSM中有45例NAC术后维持存活能力;3例NAC部分丧失存活能力。

结论

对于经过仔细筛选的患者,保乳手术是一种合理的选择。

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