Stacey C M, Munday P E, Taylor-Robinson D, Thomas B J, Gilchrist C, Ruck F, Ison C A, Beard R W
Jefferiss Wing, St Mary's Hospital, Paddington, London, UK.
Br J Obstet Gynaecol. 1992 Dec;99(12):994-9. doi: 10.1111/j.1471-0528.1992.tb13705.x.
To study the microbiology and long term prognosis of pelvic inflammatory disease (PID).
A prospective study of women with laparoscopically confirmed PID.
Teaching hospital in central London.
23 women with PID.
Microbiological investigations at the time of diagnosis and at follow up; subsequent fertility and the occurrence of pelvic pain.
PID diagnosed by laparoscopy was regarded as moderate to severe in 15 cases. Neisseria gonorrhoeae, Chlamydia trachomatis, Mycoplasma hominis and Ureaplasma urealyticum or a combination of these micro-organisms were detected most frequently in the cervix, less often in the endometrium and least in the tubes, C. trachomatis being the micro-organism found most commonly in the tubes. There was serological evidence of acute chlamydial infection in 13 of 20 cases in which paired sera were available and a serological response to M. hominis in 9 of 12 cases in which it was possible to evaluate the results. On the basis of microbiological and serological results, C. trachomatis appeared to be the most important aetiological agent in 10 cases, N. gonorrhoeae in four cases, M. hominis in three cases and U. urealyticum in none; in five cases, two of these micro-organisms appeared to be of equal importance. After 1 to 3 years, 33% of the women were having difficulty conceiving and 56% continued to complain of pelvic pain.
It is difficult to be certain of the infectious cause of PID in any given case. However, the evidence that N. gonorrhoeae and C. trachomatis are pathogens is very strong. M. hominis may be responsible for a few cases on its own or together with other micro-organisms.
研究盆腔炎（PID）的微生物学情况及长期预后。
对经腹腔镜确诊为PID的女性进行前瞻性研究。
伦敦市中心的教学医院。
23例PID女性患者。
诊断时及随访时的微生物学检查；后续的生育情况及盆腔疼痛的发生情况。
经腹腔镜诊断的PID中，15例被视为中重度。淋病奈瑟菌、沙眼衣原体、人型支原体和解脲脲原体或这些微生物的组合在宫颈中最常被检测到，在子宫内膜中较少见，在输卵管中最少见，沙眼衣原体是在输卵管中最常发现的微生物。在20例有配对血清的病例中，13例有急性衣原体感染的血清学证据，在12例可评估结果的病例中，9例有人型支原体的血清学反应。根据微生物学和血清学结果，沙眼衣原体在10例中似乎是最重要的病原体，淋病奈瑟菌在4例中是最重要的病原体，人型支原体在3例中是最重要的病原体，解脲脲原体在任何病例中均未被视为最重要的病原体；在5例中，这些微生物中的两种似乎具有同等重要性。1至3年后，33%的女性受孕困难，56%的女性仍诉说有盆腔疼痛。
在任何特定病例中，很难确定PID的感染原因。然而，淋病奈瑟菌和沙眼衣原体是病原体的证据非常确凿。人型支原体可能单独或与其他微生物一起导致少数病例。
