Barnes C J, Vadlamudi R K, Kumar R
Department of Molecular and Cellular Oncology, University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, Texas 77030, USA.
Cell Mol Life Sci. 2004 Feb;61(3):281-91. doi: 10.1007/s00018-003-3222-5.
The steroid hormone estrogen and signaling from its receptors are increasingly recognized as critical mediators of a variety of organ-specific biological processes. Recent advances in the identification and functional characterization of novel estrogen receptor interacting proteins clearly show the complexity of hormonal signaling regulation, but may also contribute to our understanding of the roles of estrogen signaling in normal physiology and the pathobiology of human disease.
类固醇激素雌激素及其受体发出的信号日益被视为多种器官特异性生物学过程的关键介质。新型雌激素受体相互作用蛋白的鉴定及其功能特性的最新进展清楚地表明了激素信号调节的复杂性，但也可能有助于我们理解雌激素信号在正常生理学和人类疾病病理生物学中的作用。
