Olson C R, Musil S Y
Department of Anatomy, College of Dental Surgery, University of Maryland, Baltimore 21201.
Cereb Cortex. 1992 Nov-Dec;2(6):485-502. doi: 10.1093/cercor/2.6.485.
The posterior cingulate cortex of the cat is strongly linked to cortical areas with sensory and oculomotor functions. We have now recorded from feline posterior cingulate neurons in order to determine whether they are active in conjunction with sensory events and eye movements. The results described here are based on monitoring the electrical activity of 195 single neurons in the posterior cingulate cortex of three cats equipped with surgically implanted scleral search coils and trained to fixate visual targets. Posterior cingulate neurons carry tonic orbital position signals and are phasically active in conjunction with saccadic eye movements. Activity related to eye movements and gaze is attenuated but not abolished by the elimination of visual feedback. Posterior cingulate neurons also are responsive to visual, auditory, and somatosensory stimulation. Systematic testing with visual stimuli revealed that responses are sharply reduced due to refractoriness at rates of stimulation greater than a few per second. These results conform to the theory that posterior cingulate cortex is involved in processes underlying visuospatial cognition.
猫的后扣带回皮层与具有感觉和动眼功能的皮层区域紧密相连。我们现在记录了猫后扣带回神经元的活动，以确定它们是否在感觉事件和眼动过程中活跃。这里描述的结果基于对三只通过手术植入巩膜搜索线圈并训练注视视觉目标的猫的后扣带回皮层中195个单神经元的电活动监测。后扣带回神经元携带持续性眼眶位置信号，并在眼球快速运动时呈现阶段性活跃。与眼动和注视相关的活动在消除视觉反馈后会减弱但不会消失。后扣带回神经元也对视觉、听觉和体感刺激有反应。用视觉刺激进行的系统测试表明，由于刺激频率高于每秒几次时的不应期，反应会急剧减少。这些结果符合后扣带回皮层参与视觉空间认知基础过程的理论。
