Carini M, Serni S, Scelzi S, Lapini A, Selli C, Stefanucci S, Betti E, Del Popolo G
Department of Urology, University of Florence, Italy.
Eur Urol. 1992;22(2):99-105. doi: 10.1159/000474733.
Since January 1985, orthotopic ileal bladder substitution after radical cystectomy was performed in 64 male patients. The Camey I procedure was performed in 35 patients (group 1) and the Studer procedure in 29 (group 2). Clinical, metabolic and urodynamic evaluation was performed at regular intervals with a mean follow-up of 27 months for group 1 and 13.6 months for group 2. Patients with a Camey I bladder reconstruction presented smaller capacity and higher intraluminal pressure resulting in shorter voiding intervals and a practically uniform presence of enuresis, as opposed to those reconstructed with the Studer procedure. The incidence of ureteral reflux was also higher in group 1. Metabolic studies in both groups revealed a slight metabolic acidosis which was treated with oral alkalinization. It is concluded that detubularization of the terminal ileum creates a more favorable low-pressure reservoir.
自1985年1月起,64例男性患者在根治性膀胱切除术后接受了原位回肠膀胱替代术。35例患者采用Camey I术式(第1组),29例采用Studer术式(第2组)。定期进行临床、代谢及尿动力学评估,第1组平均随访27个月,第2组平均随访13.6个月。与采用Studer术式重建的患者相比,采用Camey I膀胱重建的患者膀胱容量较小、腔内压力较高,导致排尿间隔时间较短且几乎均有遗尿现象。第1组输尿管反流的发生率也较高。两组的代谢研究均显示有轻度代谢性酸中毒,经口服碱化治疗。结论是末段回肠去管化可形成更有利的低压储尿囊。