Lovren F, Gaon I D, Bobarević B
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Sarajevo, Bosnia/Herzegowina.
Pharmazie. 1992 Oct;47(10):773-6.
This work describes the synthesis of 2-methyl-3-carboethoxy-5-pyrrolinone which was then allowed to react with aromatic aldehydes, nitromethines, benzendiazonium salts, hydrazine and amines. Several of the products have shown good results in preliminary antimicrobial and antifungal tests.
这项工作描述了2-甲基-3-乙氧羰基-5-吡咯啉酮的合成,然后使其与芳香醛、硝基亚甲基、苯重氮盐、肼和胺反应。其中几种产物在初步的抗菌和抗真菌测试中显示出良好的结果。