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The molecular biology of the porcine paramyxovirus LPMV.

作者信息

Linné T, Berg M, Bergvall A C, Hjertner B, Moreno-López J

机构信息

Department of Veterinary Microbiology, Swedish University of Agricultural Science, Uppsala.

出版信息

Vet Microbiol. 1992 Nov;33(1-4):263-73. doi: 10.1016/0378-1135(92)90054-w.

DOI:10.1016/0378-1135(92)90054-w
PMID:1481359
Abstract

Protein and genomic studies of a previously uncharacterized porcine paramyxovirus (designated LPMV) confirmed that it was a member of the paramyxovirus genus. The nucleotide sequences and deduced amino acids of the complete P-gene, M-gene, F-gene and HN-gene as well as the intergenic sequences have been determined. Comparative sequence analysis of the M-gene of LPMV revealed the closest relationship of LPMV was to human mumps virus with a homology of 46% and 55% at the amino acid and nucleotide levels respectively. The P-gene of LPMV is transcribed to V protein mRNA and by editing of the gene to the P protein mRNA. The LPMV P-gene has the coding capacity for an additional protein of 126 amino acids, a C protein.

摘要

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