Khlebnikov V S, Vetchinin S S, Grechko G K, Averina A A, Golovlev I R, Averin S F, Zhemchugov V E, Konovalov S I, Anisimov G A, Afanas'ev S S
Zh Mikrobiol Epidemiol Immunobiol. 1992(9-10):67-70.
The preventive activity of five monoclonal antibodies (McAb) in experimental tularemia was evaluated. McAb produced by hybridoma FB11-k (IgG2a), specific to F. tularensis lipopolysaccharide, prevented the death of mice and guinea pigs infected with F. tularensis virulent strain 503 of the holarctic subspecies.
评估了五种单克隆抗体(McAb)在实验性兔热病中的预防活性。由杂交瘤FB11-k产生的、对土拉弗朗西斯菌脂多糖具有特异性的McAb(IgG2a),可预防感染全北区亚种土拉弗朗西斯菌强毒株503的小鼠和豚鼠死亡。