[The determination of the antigenic determinant of protective monoclonal antibodies specific to the Francisella tularensis lipopolysaccharide].
作者信息
Khlebnikov V S, Golovlev I R, Tokhtamysheva N V, Averin S F, Kulevatskiĭ D P, Grechko G K, Averina A A, Vetchinin S S
出版信息
Zh Mikrobiol Epidemiol Immunobiol. 1993 Jan-Feb(1):83-8.
PMID:7520655
Abstract
F. tularensis lipopolysaccharide (LPS) was studied with the use of monoclonal antibodies (McAb) having protective properties. The binding site of these McAb (IgG2a) is localized on the O-chain of LPS. In contrast to LPS isolated from vaccine strain 15, LPS isolated from F. tularensis cells in the R-form has no O-chains and does not interact with McAb.
摘要
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