Cunningham G A, Headon D R, Conneely O M
Department of Cell Biology, Baylor College of Medicine, Houston, TX 77030.
Biochem Biophys Res Commun. 1992 Dec 30;189(3):1725-31. doi: 10.1016/0006-291x(92)90277-r.
The complete structure of the mouse lactoferrin gene is presented. Mouse lactoferrin (mLF) is encoded by a single copy gene of approximately 30 kilobases (kb) in size. The gene is organized into 17 exons separated by 16 introns. The exons range in size from 48 base pairs (bp) to 190 bp whereas the introns range from 0.2 kb to 4.3 kb. Structural analysis of the mouse lactoferrin gene reveals that this gene shares a similar intron-exon distribution pattern with both human transferrin and chicken ovotransferrin.
本文展示了小鼠乳铁蛋白基因的完整结构。小鼠乳铁蛋白（mLF）由一个大小约为30千碱基（kb）的单拷贝基因编码。该基因由17个外显子和16个内含子组成。外显子大小从48个碱基对（bp）到190 bp不等，而内含子大小从0.2 kb到4.3 kb不等。对小鼠乳铁蛋白基因的结构分析表明，该基因与人类转铁蛋白和鸡卵转铁蛋白具有相似的内含子 - 外显子分布模式。
