通过静脉注射表面活性剂在兔子身上诱导出持续性高脂血症。
Sustained hyperlipemia induced in rabbits by means of intravenously injected surface-active agents.
作者信息
KELLNER A, CORRELL J W, LADD A T
出版信息
J Exp Med. 1951 Apr 1;93(4):373-84. doi: 10.1084/jem.93.4.373.
Abstract
The intravenous injection of the surface-active agents Tween 80 and Triton A20 into rabbits fed a normal diet resulted in marked and sustained elevations of the cholesterol, phospholipid, and total lipid content of their blood. The increase in phospholipid in general paralleled that of the blood cholesterol. The implications of the findings are briefly discussed.
摘要
给正常饮食的兔子静脉注射表面活性剂吐温80和 Triton A20，导致其血液中的胆固醇、磷脂和总脂质含量显著且持续升高。磷脂的增加总体上与血液胆固醇的增加平行。文中简要讨论了这些发现的意义。
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