Minami T, Patnaik A K
Department of Pathology, Speyer Hospital and Caspary Research Institute, New York, NY 10021.
J Am Vet Med Assoc. 1992 Dec 15;201(12):1894-6.
Enucleation was performed in 10-year-old sexually intact female mixed-breed German Shepherd Dog. Histologic examination revealed that the dog had an uveal amelanotic melanoma of the eye. The tumor consisted of anaplastic cells with a high mitotic index, indicating malignancy. On examination 3 months after enucleation, the dog had difficulty breathing and nasal discharge. Radiography revealed pulmonary metastasis. The dog was euthanatized. Necropsy revealed diffuse metastasis involving various organs.
对一只10岁未绝育的雌性混种德国牧羊犬实施了眼球摘除术。组织学检查显示，这只狗患有眼部葡萄膜无黑色素黑色素瘤。肿瘤由具有高有丝分裂指数的间变细胞组成，表明为恶性肿瘤。眼球摘除术后3个月检查时，这只狗出现呼吸困难和鼻分泌物。放射检查显示有肺转移。对这只狗实施了安乐死。尸检发现有涉及多个器官的弥漫性转移。
