Schäffer E H, Funke K
Tierarztl Prax. 1985;13(3):343-59.
22 primary intraocular malignant melanomas in the dog and 5 in the cat were classified histologically. Pigmented epithelioid cells and mixed cell type melanomas with high reticulin fiber content and areas of necrosis were associated with the highest mortality rate. Metastases were found in one case each in the dog and the cat. The average age at diagnosis was 8 years in the dog and 9 years in the cat. There was no indication that intraocular melanomas are more prevalent in certain breeds. In the dog the cases were equally distributed between the sexes, whereas in the cat males were overrepresented. The most frequent location for the tumor was the uvea anterior (ciliary body). Bilateral tumor expression was observed once in a dog. In all cases the clinical diagnosis, tumor induced secondary effects, differential diagnosis and catamnesis are given.
对22例犬原发性眼内恶性黑色素瘤和5例猫原发性眼内恶性黑色素瘤进行了组织学分类。色素上皮样细胞以及网状纤维含量高且有坏死区域的混合细胞型黑色素瘤与最高死亡率相关。在犬和猫中各有1例发现转移。犬确诊时的平均年龄为8岁,猫为9岁。没有迹象表明眼内黑色素瘤在某些品种中更常见。犬的病例在两性间分布均等,而猫中雄性占比过高。肿瘤最常见的部位是眼前葡萄膜(睫状体)。在1只犬中观察到双侧肿瘤表现。所有病例均给出了临床诊断、肿瘤引起的继发效应、鉴别诊断和随访情况。