Szatmari P
Department of Psychiatry, McMaster University, Chedoke-McMaster Hospitals, Hamilton, Ontario, Canada.
J Autism Dev Disord. 1992 Dec;22(4):583-600. doi: 10.1007/BF01046329.
The objective of this literature review is to assess the validity of autistic spectrum disorders (ASD). Twenty papers were identified that adequately investigated the internal or external validity of various subtypes of ASD. At least three groups can be distinguished from autism on clinical grounds; an Asperger syndrome subtype, and two atypical subtypes characterized by low IQ and high IQ. However, the evidence that these clinical distinctions carry inferences with respect to etiology, clinical course, and treatment is only suggestive. Nevertheless, the specification of several ASD subtypes might promote further research and resolve many of the nosologic issues with respect to the classification of pervasive developmental disorders (PDDs).
本综述的目的是评估自闭症谱系障碍（ASD）的有效性。共检索到20篇对ASD各亚型的内部或外部有效性进行充分研究的论文。基于临床依据，至少可从自闭症中区分出三组；阿斯伯格综合征亚型，以及以低智商和高智商为特征的两种非典型亚型。然而，这些临床差异在病因、临床病程和治疗方面具有推断性的证据仅具有提示性。尽管如此，对几种ASD亚型的明确划分可能会促进进一步的研究，并解决广泛性发育障碍（PDD）分类方面的许多疾病分类学问题。
