Uehara S, Yasuda I, Takeya K, Itokawa H
Tokyo Metropolitan Research Laboratory of Public Health, Japan.
Yakugaku Zasshi. 1992 Nov;112(11):817-23. doi: 10.1248/yakushi1947.112.11_817.
The fresh rhizomes of Curcuma xanthorrhiza Roxb. were investigated for terpenoids and curcuminoids. Nine sesquiterpenoids, alpha-curcumene (1), arturmerone (2), xanthorrhizol (3), germacrone (4), beta-curcumene (6), beta-sesquiphellandrene (9), curzerenone (10), alpha-turmerone (11) and beta-turmerone (12), and three curcuminoids, curcumin (7), mono-demethoxycurcumin (8) and bis-demethoxycurcumin (13), were isolated and one monoterpenoid, camphor (5), was identified by capillary GC-MS. Four species of C. xanthorrhiza could be classified into two chemotypes by their bisabolane-type sesquiterpenoid compositions. The first type contained large amounts of 2, 11 and 12 (CX I type). The second type contained large amounts of 1, 3 and 6, and none of 2, 9, 11 and 12 (CX II type). These two chemotypes, CX I type and CX II type, were compared with the two chemotypes of C. longa L., CL I type and CL II type, on their contents by capillary GC and HPLC analysis. It was found that all of them contained curcuminoids, 7, 8 and 13 and large amounts of various bisabolane-type sesquiterpenoids.
对莪术新鲜根茎中的萜类化合物和姜黄素类化合物进行了研究。分离出9种倍半萜类化合物，即α-姜黄烯（1）、莪术酮（2）、莪术醇（3）、吉马酮（4）、β-姜黄烯（6）、β-倍半水芹烯（9）、莪术二酮（10）、α-姜黄酮（11）和β-姜黄酮（12），以及3种姜黄素类化合物，即姜黄素（7）、单去甲氧基姜黄素（8）和双去甲氧基姜黄素（13），并通过毛细管气相色谱-质谱联用仪鉴定出1种单萜类化合物，即樟脑（5）。根据其没药烷型倍半萜类化合物的组成，4种莪术可分为2种化学型。第一种类型含有大量的2、11和12（CX I型）。第二种类型含有大量的1、3和6，不含2、9、11和12（CX II型）。通过毛细管气相色谱和高效液相色谱分析，将这两种化学型，即CX I型和CX II型，与姜黄的两种化学型，即CL I型和CL II型，在含量上进行了比较。结果发现，它们都含有姜黄素类化合物7、8和13以及大量的各种没药烷型倍半萜类化合物。
