Kiwerski J
Kliniki Rehabilitacji AM, Warszawie.
Neurol Neurochir Pol. 1992 Jul-Aug;26(4):518-27.
The clinical usefulness of dexamethasone administered early after injury to the spinal cord is assessed comparing the results of treatment in 269 cases receiving dexamethasone and in 256 controls not receiving corticosteroids. In cases of complete as well as incomplete severing of the cord treated with dexamethasone, the results were better, both qualitatively and quantitatively. However, some increase was noted in the incidence of complications, such as gastrointestinal bleeding and delayed wound healing. Good results demonstrated in this analysis suggest the necessity of widespread administration of corticosteroids within the first hours after cord injury.
通过比较269例接受地塞米松治疗的患者和256例未接受皮质类固醇治疗的对照组的治疗结果，评估脊髓损伤后早期给予地塞米松的临床效用。在接受地塞米松治疗的脊髓完全和不完全横断病例中，结果在质量和数量上都更好。然而，注意到并发症的发生率有所增加，如胃肠道出血和伤口愈合延迟。该分析中显示的良好结果表明在脊髓损伤后的最初几小时内广泛使用皮质类固醇的必要性。
