Altermatt H J, Gebbers J O, Müller C, Arnold W, Laissue J
Institute of Pathology, University of Bern, Switzerland.
ORL J Otorhinolaryngol Relat Spec. 1992;54(4):173-8. doi: 10.1159/000276294.
Modern immunohistochemical methods allow a functional characterization of the human endolymphatic sac (ES) and its associated cell populations. The currently available immunohistochemical data on the extraosseous part of the human ES support the assumption that the epithelium is metabolically active and capable of both secretion and absorption. The reactivity of some epithelial cells with antibodies against neuroendocrine antigens implies a paracrine activity of the human ES. Further results provide evidence for a possible role of the human ES in inner ear immune defense and indicate a putative functional relationship of the human ES to the common mucosa-associated immune system.
现代免疫组织化学方法能够对人类内淋巴囊（ES）及其相关细胞群体进行功能表征。目前有关人类ES骨外部分的免疫组织化学数据支持这样一种假设，即上皮具有代谢活性，具备分泌和吸收能力。一些上皮细胞与抗神经内分泌抗原抗体的反应性表明人类ES具有旁分泌活性。进一步的结果为人类ES在内耳免疫防御中的可能作用提供了证据，并表明人类ES与常见的黏膜相关免疫系统之间存在假定的功能关系。
