Zúñiga M, Aguado J M, Vada J
Department of Internal Medicine, Marqués de Valdecilla National Hospital, Santander, Spain.
Q J Med. 1992 Nov-Dec;85(307-308):911-5.
A few cases of Listeria meningitis in healthy individuals have been recorded in the world literature. The lack of a prolonged follow-up in most of these cases makes it difficult to exclude the existence of an underlying disease. The clinical and CSF data of four previously healthy patients with meningitis due to Listeria monocytogenes are presented. These patients were followed prospectively over 2-6 years; during this time none developed any disease associated with immunosuppression, including HIV infection, and none died. Listeria meningitis in an otherwise healthy person is, therefore, not always a sign of underlying immunosuppressive disease, and does not necessarily have a poor prognosis.
世界文献中已记录了几例健康个体患李斯特菌性脑膜炎的病例。这些病例大多缺乏长期随访，因此难以排除潜在疾病的存在。本文介绍了4例先前健康、由单核细胞增生李斯特菌引起脑膜炎患者的临床和脑脊液数据。对这些患者进行了2至6年的前瞻性随访；在此期间，没有一人患上任何与免疫抑制相关的疾病，包括艾滋病毒感染，也没有一人死亡。因此，原本健康的人患李斯特菌性脑膜炎并不总是潜在免疫抑制疾病的迹象，也不一定预后不良。
