Versino M, Castelnovo G, Bergamaschi R, Romani A, Cosi V
Instituto Neurologico C. Mondino, Università di Pavia.
Boll Soc Ital Biol Sper. 1992 Jun;68(6):387-94.
We adopted the estimate of the intraclass coefficient of reliability, R, to evaluate the reliability of saccadic eye movements quantitative analysis. At a one-week interval we recorded refixative saccadic eye movements twice from fifteen healthy subjects by means of the binocular electrooculographic technique. R was computed for the constants and the slopes of the amplitude/duration and the amplitude/peak velocity relationships, for the mean precision values and for the mean latency values adjusted for subject's age. Our data demonstrated that the reliability of saccade parameters is fairly good for the amplitude/peak velocity relationship, good for the precision and very good for the amplitude/duration relationship. Finally, we believe that the normal variability values we obtained can be usefully employed in neurophysiological longitudinal studies not only in normal subjects, but also in pathological condition provided the more reliable parameters and the more adequate strategies to compute normal variability values are chosen.
我们采用组内相关系数R来评估眼跳定量分析的可靠性。我们通过双眼眼电图技术，对15名健康受试者在一周的间隔内进行了两次注视性眼跳记录。计算了幅度/持续时间和幅度/峰值速度关系的常数和斜率、平均精度值以及根据受试者年龄调整后的平均潜伏期值的R。我们的数据表明，眼跳参数对于幅度/峰值速度关系的可靠性相当好，对于精度的可靠性良好，对于幅度/持续时间关系的可靠性非常好。最后，我们认为，我们获得的正常变异性值不仅可用于正常受试者的神经生理学纵向研究，而且在选择了更可靠的参数和更合适的计算正常变异性值的策略的情况下，也可用于病理状况的研究。
