Rehák J, Karhan J
Ocní klinika LF UP, Olomouc.
Cesk Oftalmol. 1992 Dec;48(6):440-6.
The authors evaluate a group of 44 eyes treated by panretinal photocoagulation by means of an argon laser on account of proliferative diabetic retinopathy. Complete regression of neovascularizations was achieved in 64%, partial regression in 23%, treatment failed in 13%. The resulting visual acuity of 6/12 or better was achieved in 57%, at least stabilization of visual acuity was achieved in 80%, the mean follow-up period being 2.3 years. The results of treatment with an argon laser was analyzed also separately for proliferative diabetic retinopathies of different grades. The authors confirm that advanced stages of proliferative diabetic retinopathy respond more poorly to panphotocoagulation and explain this by an assumed certain grade of autonomy in very advanced proliferative diabetic retinopathy. Therapeutic failure was observed only in a group of eyes with very advanced proliferative retinopathy. The authors also confirm the observation, that if a positive response to laser therapy develops within 3-6 weeks, this is a favourable prognostic sign. In neovascularizations of the retina they observed a more favourable response to panphotocoagulation than in neovascularizations on the disc of the optic nerve.
作者评估了一组因增殖性糖尿病视网膜病变而接受氩激光全视网膜光凝治疗的44只眼睛。64%的新生血管完全消退,23%部分消退,13%治疗失败。57%的患者最终视力达到6/12或更好,80%的患者至少实现了视力稳定,平均随访期为2.3年。还分别分析了不同等级增殖性糖尿病视网膜病变的氩激光治疗结果。作者证实,增殖性糖尿病视网膜病变的晚期对全视网膜光凝反应较差,并认为这是由于非常晚期的增殖性糖尿病视网膜病变具有一定程度的自主性所致。仅在一组非常晚期增殖性视网膜病变的眼睛中观察到治疗失败。作者还证实了这一观察结果,即如果在3至6周内对激光治疗产生阳性反应,这是一个良好的预后迹象。他们观察到,视网膜新生血管对全视网膜光凝的反应比对视神经盘新生血管的反应更有利。