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戒除摇头丸:关于人们停止服用该药物的原因及其后续心理健康状况的调查。

Quitting ecstasy: an investigation of why people stop taking the drug and their subsequent mental health.

作者信息

Verheyden Suzanne L, Maidment Rachel, Curran H Valerie

机构信息

Clinical Psychopharmacology Unit, Clinical Health Psychology, University College London, London, UK.

出版信息

J Psychopharmacol. 2003 Dec;17(4):371-8. doi: 10.1177/0269881103174014.

Abstract

The regular use of ecstasy (3,4-methylenedioxymethamphetamine, MDMA) has been associated with depressed mood, anxiety and hostility, but it is not known whether such effects persist after people stop using the drug. Furthermore, little is known about what factors might influence the decision to quit using MDMA. The aim of the present study was to examine the reasons why ex-users had stopped using this drug and to assess their current levels of depression, anxiety, anger and aggression. Telephone interviews were conducted with people who used to take MDMA on a regular basis but who no longer used the drug. The participants comprised sixty-six ex-users who used to take MDMA regularly (at least once every 2 months over a period of at least 1 year), but who had not taken MDMA for at least 1 year (average 3 years). Participants were asked about why they had quit MDMA. They also completed questionnaires to assess trait mood. Ex-users could be divided into two groups based on their reason for quitting: (i) those who had quit for mental health reasons and (ii) those who had quit for circumstantial reasons. Approximately half of those in the mental health group scored in the range for clinical depression. In that group, current levels of depression and anxiety correlated significantly with the cumulative amount of MDMA that they had taken several years previously. These findings suggest that some users may either be more vulnerable to the adverse effects of MDMA or have pre-existing mental health problems for which they self-medicate by using ecstasy. The present study shows that some ex-users experience an impairment to mental health that persists for years after they stop using this drug.

摘要

经常使用摇头丸(3,4-亚甲基二氧甲基苯丙胺,MDMA)与情绪低落、焦虑和敌意有关,但人们尚不清楚在停止使用该药物后这些影响是否依然存在。此外,对于哪些因素可能影响停止使用MDMA的决定,人们了解甚少。本研究的目的是调查曾经使用过MDMA的人停止使用该药物的原因,并评估他们目前的抑郁、焦虑、愤怒和攻击性水平。对曾经经常服用MDMA但现在不再使用该药物的人进行了电话访谈。参与者包括66名曾经经常使用MDMA(在至少1年的时间里,至少每2个月使用一次)但至少有1年未服用MDMA(平均3年)的曾经使用者。参与者被问及他们停止使用MDMA的原因。他们还完成了问卷以评估特质情绪。曾经使用者可根据其停止使用的原因分为两组:(i)因心理健康原因而停止使用的人,以及(ii)因环境因素而停止使用的人。心理健康组中约有一半人的得分处于临床抑郁范围内。在该组中,目前的抑郁和焦虑水平与他们几年前服用的MDMA累计量显著相关。这些发现表明,一些使用者可能要么更容易受到MDMA不良反应的影响,要么本身就存在心理健康问题,而他们通过使用摇头丸进行自我治疗。本研究表明,一些曾经使用者在停止使用这种药物后多年仍经历心理健康损害。

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