MacMathuna P, O'Connor M K, Weir D G, Keeling P W
Department of Clinical Medicine, Trinity College Medical School, St James' Hospital, Dublin.
Gut. 1992 Dec;33(12):1671-4. doi: 10.1136/gut.33.12.1671.
The accuracy of non-invasive radionuclide angiography in detecting portal vein occlusion was assessed in 61 patients--10 with portal vein occlusion confirmed by conventional portography, 25 with chronic liver disease and a patent portal vein (mild = 12, severe = 13), and 26 with normal liver function, who served as controls. The median percentage portal venous flow for the portal vein occlusion group was 8% (range 1-30) (consistent with negligible flow) compared with 78% (52-87) for control subjects (p < 0.005) and 68% (61-80) and 49% (23-59) respectively for patients with mild and severe liver disease (p < 0.001 and p < 0.005). At a portal venous inflow of < 20%, the procedure had a specificity of 100% and sensitivity of 90% in diagnosing portal vein occlusion. Non-invasive radionuclide angiography provides a safe and accurate screening method for evaluating portal vein patency or occlusion in the investigation of portal hypertension or before liver transplantation.
对61例患者进行了无创放射性核素血管造影检测门静脉闭塞的准确性评估，其中10例经传统门静脉造影证实存在门静脉闭塞，25例患有慢性肝病且门静脉通畅（轻度12例，重度13例），26例肝功能正常者作为对照。门静脉闭塞组门静脉血流百分比中位数为8%（范围1 - 30）（与可忽略不计的血流一致），而对照组为78%（52 - 87）（p < 0.005），轻度和重度肝病患者分别为68%（61 - 80）和49%（23 - 59）（p < 0.001和p < 0.005）。当门静脉流入量<20%时，该方法诊断门静脉闭塞的特异性为100%，敏感性为90%。无创放射性核素血管造影为评估门静脉高压症或肝移植术前门静脉通畅或闭塞情况提供了一种安全、准确的筛查方法。
