Johnson D R, O'Higgins P, McAndrew T J, Kida M Y
Department of Anatomy, University of Leeds, UK.
J Anat. 1992 Jun;180 ( Pt 3)(Pt 3):507-14.
The shapes of cervical and upper thoracic vertebrae from large samples of 2 inbred strains of mice and their F1 offspring were examined using Fourier analysis to investigate in detail the distributions and magnitudes of differences in vertebral shape between different strains of mice, the relationships between parents and offspring and any differences in the inheritance of vertebral shape between successive vertebral levels. Consistent with the findings of an earlier study there was evidence for considerable differences between vertebral levels in the degree to which offspring resemble one or other parent. The results demonstrate that the inheritance of vertebral morphology conforms to a model in which F1s between inbred strains form a triangular relationship with their parents. Furthermore, this relationship varies between vertebral levels. The significance of these findings is considered in relation to the understanding of the mechanisms of character inheritance and evolution and some new directions for research into vertebral column morphogenesis are proposed.
使用傅里叶分析检查了来自2个近交系小鼠及其F1后代的大样本中的颈椎和上胸椎形状，以详细研究不同品系小鼠之间椎骨形状差异的分布和大小、亲子关系以及连续椎体水平之间椎骨形状遗传的任何差异。与早期研究结果一致，有证据表明后代与父母一方或另一方相似的程度在椎体水平之间存在相当大的差异。结果表明，椎骨形态的遗传符合一个模型，即近交系之间的F1与其亲本形成三角关系。此外，这种关系在不同椎体水平之间有所不同。结合对性状遗传和进化机制的理解来考虑这些发现的意义，并提出了一些关于脊柱形态发生研究的新方向。
