Johnson D R, O'Higgins P, McAndrew T J
Department of Anatomy, University of Leeds, West Yorkshire, UK.
J Anat. 1989 Apr;163:49-55.
Videodigitised outlines of C6, C7, T1 and T2 vertebrae from 23 mice carrying the mutant gene undulated (un/un) and normal littermates (+/un) have been examined by Fourier analysis. There were large differences in shape between C6 vertebrae, smaller but significant differences in C7 and insignificant differences between T1s. The situation in T2 was complicated by the effects of the genetic background, but the effect of undulated was still significant. We conclude that the undulated gene shows significant pleiotropy in its effects even over this short length of the vertebral column.
对23只携带突变基因波状(un/un)的小鼠及其正常同窝小鼠(+/un)的第6、7、1和2胸椎的视频数字化轮廓进行了傅里叶分析。第6胸椎在形状上存在较大差异,第7胸椎差异较小但显著,第1胸椎之间差异不显著。第2胸椎的情况因遗传背景的影响而复杂,但波状基因的影响仍然显著。我们得出结论,即使在如此短的脊柱长度上,波状基因的影响也表现出显著的多效性。