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基因起伏(un)对家鼠(小家鼠)颈椎和上胸椎形态的影响。

The effect of the gene undulated (un) on the shape of cervical and upper thoracic vertebrae in the house mouse (Mus musculus).

作者信息

Johnson D R, O'Higgins P, McAndrew T J

机构信息

Department of Anatomy, University of Leeds, West Yorkshire, UK.

出版信息

J Anat. 1989 Apr;163:49-55.

PMID:2606780
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1256514/
Abstract

Videodigitised outlines of C6, C7, T1 and T2 vertebrae from 23 mice carrying the mutant gene undulated (un/un) and normal littermates (+/un) have been examined by Fourier analysis. There were large differences in shape between C6 vertebrae, smaller but significant differences in C7 and insignificant differences between T1s. The situation in T2 was complicated by the effects of the genetic background, but the effect of undulated was still significant. We conclude that the undulated gene shows significant pleiotropy in its effects even over this short length of the vertebral column.

摘要

对23只携带突变基因波状(un/un)的小鼠及其正常同窝小鼠(+/un)的第6、7、1和2胸椎的视频数字化轮廓进行了傅里叶分析。第6胸椎在形状上存在较大差异,第7胸椎差异较小但显著,第1胸椎之间差异不显著。第2胸椎的情况因遗传背景的影响而复杂,但波状基因的影响仍然显著。我们得出结论,即使在如此短的脊柱长度上,波状基因的影响也表现出显著的多效性。

相似文献

1
The effect of the gene undulated (un) on the shape of cervical and upper thoracic vertebrae in the house mouse (Mus musculus).基因起伏(un)对家鼠(小家鼠)颈椎和上胸椎形态的影响。
J Anat. 1989 Apr;163:49-55.
2
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引用本文的文献

1
The inheritance of vertebral shape in the mouse. II. A study using Fourier analysis to examine the inheritance of patterns of vertebral variation in the cervical and upper thoracic vertebral column.小鼠椎骨形状的遗传。II. 一项使用傅里叶分析研究颈椎和上胸椎椎体变异模式遗传的研究。
J Anat. 1993 Feb;182 ( Pt 1)(Pt 1):65-73.
2
The effect of diet on bone shape in the mouse.饮食对小鼠骨骼形态的影响。
J Anat. 1990 Oct;172:213-20.
3
The inheritance of vertebral shape in the mouse. I. A study using Fourier analysis to examine patterns of inheritance in the morphology of cervical and upper thoracic vertebrae.小鼠椎体形状的遗传。I. 一项使用傅里叶分析研究颈椎和上胸椎形态遗传模式的研究。
J Anat. 1992 Jun;180 ( Pt 3)(Pt 3):507-14.

本文引用的文献

1
Measurement of biological shape: a general method applied to mouse vertebrae.
J Embryol Exp Morphol. 1985 Dec;90:363-77.
2
The clonal model of vertebral column development: a reinvestigation of vertebral shape using Fourier analysis.
J Embryol Exp Morphol. 1986 Jul;96:171-82.
3
The effect of replicated selection for body weight in mice on vertebral shape.
Genet Res. 1988 Apr;51(2):129-35. doi: 10.1017/s0016672300024149.