甲状腺功能减退症与原发性开角型青光眼。
Hypothyroidism and primary open-angle glaucoma.
作者信息
Muñoz-Negrete F J, Rebolleda G, Almodóvar F, Díaz B, Varela C
机构信息
Department of Ophthalmology, Ramón y Cajal Hospital, Madrid, Spain.
出版信息
Ophthalmologica. 2000 Sep-Oct;214(5):347-9. doi: 10.1159/000027518.
OBJECTIVE
To test if there is an association between hypothyroidism and primary open-angle glaucoma (POAG) and the utility of routine study of thyroid function in these patients.
METHODS
The study was conducted in a case-control fashion. Seventy-five consecutive patients with a previous diagnosis of POAG and 75 control patients were prospectively evaluated for hypothyroidism. The levels of thyroid-stimulating hormone and free thyroxin were measured.
RESULTS
Hypothyroidism was revealed in only 2 patients with previous diagnosis of POAG (2.67%) and 3 patients of the control group (4%).
CONCLUSIONS
As we have not been able to demonstrate the previously reported relationship between hypothyroidism and POAG, we cannot recommend the systematic screening for hypothyroidism in patients with POAG.
目的
检验甲状腺功能减退症与原发性开角型青光眼（POAG）之间是否存在关联，以及对这些患者进行甲状腺功能常规检查的实用性。
方法
本研究采用病例对照研究方式。对75例既往诊断为POAG的连续患者和75例对照患者进行前瞻性甲状腺功能减退症评估。测量促甲状腺激素和游离甲状腺素水平。
结果
既往诊断为POAG的患者中仅2例（2.67%）及对照组3例（4%）被发现有甲状腺功能减退症。
结论
由于我们未能证实先前报道的甲状腺功能减退症与POAG之间的关系，因此不能建议对POAG患者进行系统性甲状腺功能减退症筛查。
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