Hoffmann A, Jäger O, Peiker G, Reimann I
Institut für Klinische Pharmakologie, Friedrich-Schiller-Universität Jena, Germany.
Int J Clin Pharmacol Ther Toxicol. 1992 Nov;30(11):462-4.
In an epidemiological collaborative international study under the auspices of WHO-Euro the drug use in pregnancy was investigated in 22 countries in 14,778 women and in hospitals of three different levels. The East German state Thuringia took part according to the annual birth rate with 300 women in 3 hospitals (Jena, Gera, Greiz). In the international average, 14% of the enrolled women took no drugs during pregnancy before admission to hospital for delivery. In East Germany 44% of the women taking part in the study had no drug administration during pregnancy. The critical use of iron preparations and vitamins there has to be mentioned. Under delivery, 99% of the Thuringian women received drugs. In the puerperium the administration of ergot derivatives and of laxatives exceeds the international average and has to be critically revised, but the administration of antiinfectives in only 1/5 and of analgetics 1/3 of the international average.
在世界卫生组织欧洲区域办事处主持的一项国际流行病学合作研究中，对22个国家的14778名妇女以及三个不同级别的医院中的孕妇用药情况进行了调查。东德图林根州根据年出生率派出300名妇女参与研究，她们来自耶拿、 Gera和格雷茨的3家医院。国际平均水平显示，在入院分娩前，14%的登记妇女在孕期未使用药物。在东德，参与研究的妇女中有44%在孕期未用药。必须提及铁制剂和维生素在当地的大量使用情况。分娩时，99%的图林根州妇女接受了药物治疗。在产褥期，麦角衍生物和泻药的使用量超过国际平均水平，必须进行严格审查，但抗感染药物的使用量仅为国际平均水平的五分之一，镇痛药的使用量为三分之一。
