Liu G C, Jong Y J, Chiang C H, Yang C W
Department of Radiology, Kaohsiung Medical College, Taiwan, ROC.
Pediatr Radiol. 1992;22(8):584-6. doi: 10.1007/BF02015357.
The neurogenic myopathy of spinal muscular atrophy (SMA) is degeneration of anterior horn cells of the spinal cord and associated muscle weakness. In three patients with the severe type, according to Dubowitz's classification, magnetic resonance imaging (MRI) of the lower extremity showed severe atrophy of the entire muscle bundles of the thigh and the calf. Nine intermediate type patients had ragged atrophy of muscle bundles of the thigh and the calf with selective preservation of adductor longus muscle. Five patients with the mild type had fatty infiltration of muscle bundles and increased intermuscular fat planes. MRI was insufficient for the evaluation of cervical cord abnormalities. MRI of the lower extremity was a reliable complementary modality for the diagnosis and follow-up of SMA patients.
脊髓性肌萎缩症（SMA）的神经源性肌病是脊髓前角细胞变性及相关肌肉无力。在3例根据杜波维茨分类法属于重型的患者中，下肢磁共振成像（MRI）显示大腿和小腿的整个肌束严重萎缩。9例中间型患者大腿和小腿的肌束呈破碎状萎缩，长收肌选择性保留。5例轻型患者肌束有脂肪浸润且肌间脂肪平面增加。MRI对评估颈髓异常不足。下肢MRI是SMA患者诊断和随访的可靠补充手段。
