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[意大利女性的饮食与心血管风险]

[Diet and cardiovascular risk among women in Italy].

作者信息

Farinaro E, Panico S, Jossa F

机构信息

Istituto di Medicina Interna e Malattie Dismetaboliche, Università degli Studi, Napoli.

出版信息

Ann Ist Super Sanita. 1992;28(3):349-53.

PMID:1492732
Abstract

Coronary Heart Disease (CHD) is less common in females compared to males and geographical differences are observed in both sexes; furthermore time trend mortality in women follows the same pattern as in men suggesting that the environmental factors have similar influence in both sexes. Nutrition is an environmental factor which plays an important role in the etiology and pathogenesis of CHD. The Italian Nine Communities Study on Atherosclerosis Risk Factors analyzes the relationships between consumption of food rich in saturated fatty acids and cholesterol and a number of CHD risk factors in a sample of Italian women aged 20-59 years. The dietary habits of the participants were ascertained by a food frequency questionnaire. Intake of atherogenic food was evaluated for each participants systolic blood pressure, serum glucose, serum cholesterol increased with increasing consumption of atherogenic food (i.e. butter). Conversely, consumption of olive oil and vegetable oil was inversely associated with serum cholesterol, serum glucose and systolic blood pressure. Furthermore, calcium rich food consumption was associated with lower blood pressure. These findings were independent from any possible confounding effect of age, adiposity, alcohol intake and cigarette smoking. Data from the Intersalt Study in Italy (400 women aged 20-59 years) have clearly shown lower blood pressure levels in participants with lower intake of sodium and alcohol and higher intake of potassium. Some clinical and experimental observations suggest a possible difference in response to dietary factors in women compared to men due to the intermediate effects of the sex hormone pattern.

摘要

与男性相比,冠心病(CHD)在女性中不太常见,并且在两性中均观察到地理差异;此外,女性的时间趋势死亡率与男性遵循相同的模式,这表明环境因素对两性的影响相似。营养是一种环境因素,在冠心病的病因和发病机制中起着重要作用。意大利九社区动脉粥样硬化危险因素研究分析了20-59岁意大利女性样本中富含饱和脂肪酸和胆固醇的食物消费与一些冠心病危险因素之间的关系。参与者的饮食习惯通过食物频率问卷确定。对每位参与者评估致动脉粥样硬化食物的摄入量,随着致动脉粥样硬化食物(即黄油)摄入量的增加,收缩压、血清葡萄糖、血清胆固醇升高。相反,橄榄油和植物油的消费与血清胆固醇、血清葡萄糖和收缩压呈负相关。此外,富含钙的食物消费与较低的血压有关。这些发现独立于年龄、肥胖、酒精摄入和吸烟的任何可能混杂效应。意大利国际盐类研究(400名20-59岁女性)的数据清楚地表明,钠和酒精摄入量较低且钾摄入量较高的参与者血压水平较低。一些临床和实验观察表明,由于性激素模式的中间作用,女性与男性相比对饮食因素的反应可能存在差异。

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