DAHL L K, DOLE V P
J Exp Med. 1952 Apr;95(4):341-6. doi: 10.1084/jem.95.4.341.
RENAL CALCIFICATION, INDUCED IN RATS BY AN INJECTION OF URANIUM, IS ACCOMPLISHED IN TWO STAGES: a primary accumulation of calcium in association with anions other than phosphate and a secondary conversion of this calcium complex into a precipitate of calcium phosphate. Except for the exclusion of chondroitin sulfate, the nature of the primary anions remains undefined. The accumulation of calcium in the kidney was converted into a precipitate of minimum solubility, and thus the evidence of its primary causation was obliterated. This may well hold true of calcification at other situations.
钙首先与除磷酸盐以外的阴离子结合积累，然后这种钙复合物再二次转化为磷酸钙沉淀。除了排除硫酸软骨素外，主要阴离子的性质仍不明确。肾脏中钙的积累转化为溶解度最小的沉淀，因此其最初成因的证据被消除了。这很可能也适用于其他情况下的钙化。
