Síma P, Bilej M, Kovárů F, Vĕtvicka V, Holub M
Institute of Microbiology, Czechoslovak Academy of Sciences, Prague.
Folia Microbiol (Praha). 1992;37(5):381-5. doi: 10.1007/BF02815667.
The proliferation activity of the main cellular categories of bone marrow after infusion of 3H-thymidine was studied in nu/nu and +/+ 1-month- and 3-month-old BALB/c mice in comparison with lymphoid cells in the spleen and mesenteric lymph nodes. The stem cell defect in nu/nu mouse bone marrow is compensated by an increased proliferation in myeloid series and in agranulocytes. The increase of proliferation activity among lymphoid cells in peripheral lymphoid organs was observed only in the 3-month-old mice with a delay in the nudes.
在nu/nu和+/+ 1月龄及3月龄BALB/c小鼠中，研究了注入3H-胸腺嘧啶核苷后骨髓主要细胞类别的增殖活性，并与脾脏和肠系膜淋巴结中的淋巴细胞进行比较。nu/nu小鼠骨髓中的干细胞缺陷通过髓系和无粒细胞增殖增加得到补偿。仅在3月龄裸鼠中观察到外周淋巴器官中淋巴细胞增殖活性增加，但有延迟。
