Peyman G A, Conway M D, Karaçorlu M, Soike K F, Bhatt N, Clark L C, Hoffmann R E
School of Medicine, LSU Eye Center, New Orleans 70112.
Ophthalmic Surg. 1992 Dec;23(12):811-7.
Two preparations of silicone gels were evaluated as long-term vitreous substitutes in the vitrectomized and lensectomized eyes of primates. Both preparations were injected in liquid form and polymerized in the vitreous cavity. There was no toxic effect on the ocular structures up to 13 months after implantation. Fundus examination and fluorescein angiography were possible through the less rigid gel, whereas the preparation with higher rigidity consistently appeared cloudy.
评估了两种硅胶凝胶制剂，作为灵长类动物玻璃体切除和晶状体切除眼中的长期玻璃体替代物。两种制剂均以液体形式注射并在玻璃体腔内聚合。植入后长达13个月对眼部结构均无毒性作用。通过较软的凝胶可以进行眼底检查和荧光素血管造影，而硬度较高的制剂始终显得浑浊。
