Deobhakta Avnish, Rosen Richard
Department of Ophthalmology New York Eye and Ear Infirmary of Mount Sinai Icahn School of Medicine at Mount Sinai, New York, USA.
Curr Ophthalmol Rep. 2020 Sep;8(3):144-151. doi: 10.1007/s40135-020-00247-9. Epub 2020 Jul 4.
In this article, the current use and limitations of existing retinal tamponades are discussed. Potential novel developments that address those limitations are subsequently highlighted, along with areas of future improvements.
While retinal tamponades have existed for decades and improved the treatment of retinal detachments, many problems still exist with their use, including inadequate tamponade of the inferior retina, toxicity from retained heavy liquids, glaucoma, and keratopathy, among others. New advancements in the components of heavy liquids and vitreous substitutes aim to mitigate those issues.
Existing retinal tamponades, including perflurocarbon heavy liquids, fluorinated gases, and silicone oil, have specific limitations that cause potentially avoidable morbidity. New developments, such as heavy silicone oil, novel vitreous gels, and future avenues of approach, such as potentially reabsorbing heavy liquids may help increase our ability to treat retinal detachments with fewer complications.
本文讨论了现有视网膜填充剂的当前应用及局限性。随后重点介绍了针对这些局限性的潜在新进展以及未来的改进方向。
虽然视网膜填充剂已存在数十年并改善了视网膜脱离的治疗，但在其使用过程中仍存在许多问题，包括视网膜下方填充不足、残留重液的毒性、青光眼和角膜病变等。重液和玻璃体替代物成分的新进展旨在缓解这些问题。
现有的视网膜填充剂，包括全氟碳重液、氟化气体和硅油，存在特定局限性，会导致潜在的可避免的发病率。新进展，如重硅油、新型玻璃体凝胶，以及未来的方法途径，如可能可吸收的重液，可能有助于提高我们治疗视网膜脱离且减少并发症的能力。
