Murphy W M, Deana D G
University of Tennessee, Memphis.
Mod Pathol. 1992 May;5(3):240-3.
This report describes four cases in which a malignant transitional cell neoplasm initially manifested as small nests and abortive tubules infiltrating the lamina propria. Many of the tumor cells were only slightly atypical but careful examination revealed at least some significantly anaplastic cells in every case, the degree of cellular atypia tending to parallel the depth of invasion. Despite the initial impression of a benign lesion resembling a proliferation of Brunn's nests, these carcinomas tended to be persistent and aggressive.
本报告描述了4例恶性移行细胞瘤病例，其最初表现为浸润固有层的小巢状结构和发育不全的小管。许多肿瘤细胞仅有轻微异型性，但仔细检查发现每例中至少有一些明显间变的细胞，细胞异型程度往往与浸润深度平行。尽管最初印象是良性病变，类似布伦巢增生，但这些癌往往具有持续性和侵袭性。
