门控正电子发射断层扫描（PET）与磁共振成像（MRI）在评估冠心病患者左心室功能方面的比较。
Comparison of gated PET with MRI for evaluation of left ventricular function in patients with coronary artery disease.
作者信息
Slart Riemer H J A, Bax Jeroen J, de Jong Richard M, de Boer Jaep, Lamb Hildo J, Mook Piet H, Willemsen Antoon T M, Vaalburg Willem, van Veldhuisen Dirk J, Jager Pieter L
机构信息
Department of Nuclear Medicine, Groningen University Medical Center, Hanzeplein 1, PO Box 30001, 9700 RB Groningen, The Netherlands.
出版信息
J Nucl Med. 2004 Feb;45(2):176-82.
UNLABELLED
The aim of this study was to compare left ventricular (LV) volumes and regional wall motion determined by PET with those determined by the reference technique, cardiovascular MRI.
METHODS
LV end-diastolic volume (LVEDV), LV end-systolic volume (LVESV), and LV ejection fraction (LVEF) were measured and regional wall motion was scored in 38 patients with chronic coronary artery disease by both gated (18)F-FDG PET and MRI. A 9-segment model was used for PET and MRI to assess regional wall motion.
RESULTS
Good correlations were observed between MRI and gated PET for all parameters (r values ranging from 0.91 to 0.96). With PET, there was a significant but small underestimation of LVEDV and LVEF. Mean +/- SD LVEDV, LVESV, and LVEF for MRI were 131 +/- 57 mL, 91 +/- 12 mL, and 33% +/- 12%, respectively, and those for gated PET were 117 +/- 56 mL, 85 +/- 51 mL, and 30% +/- 11%, respectively. For regional wall motion, an agreement of 85% was found, with a kappa-statistic of 0.79 (95% confidence interval, 0.70-0.89; SE, 0.049).
CONCLUSION
LV volumes, LVEF, and regional wall motion can be assessed with gated (18)F-FDG PET and correlate well with these parameters assessed by MRI.
未标注
本研究的目的是比较正电子发射断层扫描（PET）测定的左心室（LV）容积和局部室壁运动与参考技术心血管磁共振成像（MRI）测定的结果。
方法
对38例慢性冠状动脉疾病患者，通过门控（18）F - 氟代脱氧葡萄糖（FDG）PET和MRI测量左心室舒张末期容积（LVEDV）、左心室收缩末期容积（LVESV）和左心室射血分数（LVEF），并对局部室壁运动进行评分。PET和MRI均采用9节段模型评估局部室壁运动。
结果
MRI和门控PET在所有参数上均呈现良好的相关性（r值范围为0.91至0.96）。PET测量时，LVEDV和LVEF存在显著但较小的低估。MRI测量的LVEDV、LVESV和LVEF的均值±标准差分别为131±57 mL、91±12 mL和33%±12%，门控PET测量的相应值分别为117±56 mL、85±51 mL和30%±11%。对于局部室壁运动，一致性为85%，kappa统计量为0.79（95%置信区间，0.70 - 0.89；标准误为0.049）。
结论
门控（18）F - FDG PET可用于评估LV容积、LVEF和局部室壁运动，且与MRI评估的这些参数具有良好的相关性。
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