• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

欧洲核医学协会(EANM)正电子发射断层扫描(PET)/计算机断层扫描(CT)心肌灌注成像操作指南。

EANM procedural guidelines for PET/CT quantitative myocardial perfusion imaging.

机构信息

Nuclear Medicine Unit, Department of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, Largo Brambilla 3, 50134, Florence, Italy.

Radiology & Molecular Imaging, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.

出版信息

Eur J Nucl Med Mol Imaging. 2021 Apr;48(4):1040-1069. doi: 10.1007/s00259-020-05046-9. Epub 2020 Nov 2.

DOI:10.1007/s00259-020-05046-9
PMID:33135093
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7603916/
Abstract

The use of cardiac PET, and in particular of quantitative myocardial perfusion PET, has been growing during the last years, because scanners are becoming widely available and because several studies have convincingly demonstrated the advantages of this imaging approach. Therefore, there is a need of determining the procedural modalities for performing high-quality studies and obtaining from this demanding technique the most in terms of both measurement reliability and clinical data. Although the field is rapidly evolving, with progresses in hardware and software, and the near perspective of new tracers, the EANM Cardiovascular Committee found it reasonable and useful to expose in an updated text the state of the art of quantitative myocardial perfusion PET, in order to establish an effective use of this modality and to help implementing it on a wider basis. Together with the many steps necessary for the correct execution of quantitative measurements, the importance of a multiparametric approach and of a comprehensive and clinically useful report have been stressed.

摘要

在过去几年中,心脏 PET 的使用,特别是定量心肌灌注 PET 的使用一直在增加,因为扫描仪越来越普及,而且多项研究令人信服地证明了这种成像方法的优势。因此,需要确定进行高质量研究的程序模式,并从这项高要求的技术中获得尽可能多的测量可靠性和临床数据。尽管该领域发展迅速,硬件和软件都在不断进步,而且新示踪剂的前景也近在咫尺,但 EANM 心血管委员会认为,以更新的文本展示定量心肌灌注 PET 的最新技术状态是合理且有用的,以便有效利用这种方式,并帮助更广泛地实施这种方式。除了正确执行定量测量所需的许多步骤外,还强调了多参数方法和全面、具有临床意义的报告的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cfe/8041709/cb29899ca6d5/259_2020_5046_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cfe/8041709/4bfe2cb25cb9/259_2020_5046_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cfe/8041709/ae84d282193f/259_2020_5046_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cfe/8041709/c0723bc86057/259_2020_5046_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cfe/8041709/b999d66e63c8/259_2020_5046_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cfe/8041709/12c4e210c0dd/259_2020_5046_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cfe/8041709/1d36faec33c0/259_2020_5046_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cfe/8041709/d4feead056d1/259_2020_5046_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cfe/8041709/61742a8f0e88/259_2020_5046_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cfe/8041709/cb29899ca6d5/259_2020_5046_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cfe/8041709/4bfe2cb25cb9/259_2020_5046_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cfe/8041709/ae84d282193f/259_2020_5046_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cfe/8041709/c0723bc86057/259_2020_5046_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cfe/8041709/b999d66e63c8/259_2020_5046_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cfe/8041709/12c4e210c0dd/259_2020_5046_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cfe/8041709/1d36faec33c0/259_2020_5046_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cfe/8041709/d4feead056d1/259_2020_5046_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cfe/8041709/61742a8f0e88/259_2020_5046_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cfe/8041709/cb29899ca6d5/259_2020_5046_Fig9_HTML.jpg

相似文献

1
EANM procedural guidelines for PET/CT quantitative myocardial perfusion imaging.欧洲核医学协会(EANM)正电子发射断层扫描(PET)/计算机断层扫描(CT)心肌灌注成像操作指南。
Eur J Nucl Med Mol Imaging. 2021 Apr;48(4):1040-1069. doi: 10.1007/s00259-020-05046-9. Epub 2020 Nov 2.
2
Clinical use of quantitative cardiac perfusion PET: rationale, modalities and possible indications. Position paper of the Cardiovascular Committee of the European Association of Nuclear Medicine (EANM).定量心肌灌注PET的临床应用:基本原理、方式及可能的适应证。欧洲核医学协会(EANM)心血管委员会立场文件
Eur J Nucl Med Mol Imaging. 2016 Jul;43(8):1530-45. doi: 10.1007/s00259-016-3317-5. Epub 2016 Feb 5.
3
Cardiac positron emission tomography imaging.心脏正电子发射断层显像
Semin Nucl Med. 2005 Jan;35(1):17-36. doi: 10.1053/j.semnuclmed.2004.09.002.
4
Integration of Quantitative Positron Emission Tomography Absolute Myocardial Blood Flow Measurements in the Clinical Management of Coronary Artery Disease.定量正电子发射断层扫描绝对心肌血流量测量在冠状动脉疾病临床管理中的整合
Circulation. 2016 May 31;133(22):2180-96. doi: 10.1161/CIRCULATIONAHA.115.018089.
5
Semi-quantitative myocardial perfusion measured by computed tomography in patients with refractory angina: a head-to-head comparison with quantitative rubidium-82 positron emission tomography as reference.计算机断层扫描测量难治性心绞痛患者的半定量心肌灌注:与作为参考的定量铷-82正电子发射断层扫描的直接比较
Clin Physiol Funct Imaging. 2017 Sep;37(5):481-488. doi: 10.1111/cpf.12322. Epub 2015 Dec 2.
6
Myocardial perfusion imaging with PET.正电子发射断层显像心肌灌注成像
Int J Cardiovasc Imaging. 2017 Jul;33(7):1021-1031. doi: 10.1007/s10554-017-1084-4. Epub 2017 Feb 10.
7
Selection of PET Camera and Implications on the Reliability and Accuracy of Absolute Myocardial Blood Flow Quantification.正电子发射断层扫描(PET)相机的选择对绝对心肌血流定量的可靠性和准确性的影响。
Curr Cardiol Rep. 2020 Aug 8;22(10):109. doi: 10.1007/s11886-020-01376-0.
8
Positron Emission Tomography in the Diagnosis and Management of Coronary Artery Disease.正电子发射断层扫描在冠状动脉疾病的诊断和管理中的应用。
Medicina (Kaunas). 2018 Jul 11;54(3):47. doi: 10.3390/medicina54030047.
9
Integrated Myocardial Perfusion Imaging Diagnostics Improve Detection of Functionally Significant Coronary Artery Stenosis by 13N-ammonia Positron Emission Tomography.整合心肌灌注成像诊断通过¹³N-氨正电子发射断层扫描改善对功能性显著冠状动脉狭窄的检测。
Circ Cardiovasc Imaging. 2016 Sep;9(9). doi: 10.1161/CIRCIMAGING.116.004768.
10
PET/CT Myocardial Perfusion Imaging Acquisition and Processing: Ten Tips and Tricks to Help You Succeed.正电子发射断层扫描(PET)/CT 心肌灌注成像采集和处理:帮助你成功的十个技巧和窍门。
Curr Cardiol Rep. 2021 Mar 11;23(5):39. doi: 10.1007/s11886-021-01476-5.

引用本文的文献

1
Coronary flow reserve increase after 4-year dapagliflozin treatment in patients with type 2 diabetes: the DAPAHEART follow-up study.达格列净治疗2型糖尿病患者4年后冠状动脉血流储备增加:DAPAHEART随访研究
Cardiovasc Diabetol. 2025 Aug 31;24(1):351. doi: 10.1186/s12933-025-02912-4.
2
Effect of a single ultra processed meal on myocardial endothelial function, adenosine mediated effects and cognitive performances.一顿超加工餐对心肌内皮功能、腺苷介导的效应及认知表现的影响。
Sci Rep. 2025 Aug 6;15(1):28671. doi: 10.1038/s41598-025-11734-z.
3
Transient ischemic dilation ratio by [N]NH PET/CT in patients with variable extent of myocardial ischemia: relevance of software package and quantification method.

本文引用的文献

1
Impact of regadenoson-induced myocardial creep on dynamic Rubidium-82 PET myocardial blood flow quantification.瑞加德松诱导的心肌蠕变对动态铷-82 PET 心肌血流定量的影响。
J Nucl Cardiol. 2019 Jun;26(3):719-728. doi: 10.1007/s12350-019-01649-4. Epub 2019 Feb 20.
2
Coronary vascular function in patients with resistant hypertension and normal myocardial perfusion: a propensity score analysis.耐治疗高血压患者的冠状动脉血管功能与正常心肌灌注:倾向评分分析。
Eur Heart J Cardiovasc Imaging. 2019 Aug 1;20(8):949-958. doi: 10.1093/ehjci/jez025.
3
Performance Characteristics of the Digital Biograph Vision PET/CT System.
[氮]NH PET/CT对不同程度心肌缺血患者的短暂性缺血性扩张率:软件包和定量方法的相关性
Int J Cardiovasc Imaging. 2025 Aug;41(8):1605-1617. doi: 10.1007/s10554-025-03468-w. Epub 2025 Jul 18.
4
F-fluorodeoxyglucose PET/CT scans for thoracic tuberculosis: current evidence and future perspectives.用于胸段脊柱结核的氟脱氧葡萄糖正电子发射断层显像/计算机断层扫描:当前证据与未来展望
Eur Respir Rev. 2025 Jun 25;34(176). doi: 10.1183/16000617.0289-2024. Print 2025 May.
5
Left ventricular diastolic inflow and myocardial flow reserve in patients with coronary artery disease: simultaneous analysis of 4D-Flow and myocardial perfusion using hybrid PETMR.冠心病患者的左心室舒张期血流及心肌血流储备:使用混合PETMR对4D血流和心肌灌注进行同步分析
Int J Cardiovasc Imaging. 2025 Apr 10. doi: 10.1007/s10554-025-03387-w.
6
N-NH myocardial perfusion imaging with reduced scan duration: a feasibility study in the era of total-body PET/CT.扫描时间缩短的 N-NH 心肌灌注成像:全身 PET/CT 时代的可行性研究
EJNMMI Phys. 2025 Mar 4;12(1):18. doi: 10.1186/s40658-025-00729-4.
7
Is cardiopulmonary transit time (CPTT) measured by using dynamic rubidium cardiac PET/CT a predictor for cardiac function?使用动态铷心肌PET/CT测量的心肺转运时间(CPTT)是否是心脏功能的预测指标?
Int J Cardiovasc Imaging. 2025 Mar;41(3):569-577. doi: 10.1007/s10554-025-03346-5. Epub 2025 Feb 14.
8
Mexican guidelines 2024 for the diagnosis and treatment of hypertrophic cardiomyopathy.《2024年墨西哥肥厚型心肌病诊断与治疗指南》
Arch Cardiol Mex. 2024;94(Supl 4):1-75. doi: 10.24875/ACM.M25000098.
9
Positron Range Correction Helps Enhance the Image Quality of Cardiac Rb PET/CT.正电子射程校正有助于提高心脏铷PET/CT的图像质量。
J Nucl Med. 2025 Mar 3;66(3):466-472. doi: 10.2967/jnumed.124.267855.
10
Recent Progress in Myocardial Perfusion Imaging Techniques.心肌灌注成像技术的最新进展
Nucl Med Mol Imaging. 2024 Dec;58(7):400-405. doi: 10.1007/s13139-024-00852-7. Epub 2024 Mar 5.
Digital Biograph Vision PET/CT 系统的性能特点。
J Nucl Med. 2019 Jul;60(7):1031-1036. doi: 10.2967/jnumed.118.215418. Epub 2019 Jan 10.
4
System evaluation of automated production and inhalation of O-labeled gaseous radiopharmaceuticals for the rapid O-oxygen PET examinations.用于快速氧-15正电子发射断层显像检查的氧-15标记气态放射性药物自动生产与吸入的系统评估。
EJNMMI Phys. 2018 Dec 19;5(1):37. doi: 10.1186/s40658-018-0236-5.
5
Dosimetry, biodistribution, and safety of flurpiridaz F 18 in healthy subjects undergoing rest and exercise or pharmacological stress PET myocardial perfusion imaging.氟吡拉达 F18 在健康受试者行静息和运动或药物负荷 PET 心肌灌注显像中的剂量学、生物分布和安全性。
J Nucl Cardiol. 2019 Dec;26(6):2018-2030. doi: 10.1007/s12350-018-01484-z. Epub 2018 Nov 28.
6
Performance Evaluation of the Vereos PET/CT System According to the NEMA NU2-2012 Standard.根据 NEMA NU2-2012 标准对 Vereos PET/CT 系统进行性能评估。
J Nucl Med. 2019 Apr;60(4):561-567. doi: 10.2967/jnumed.118.215541. Epub 2018 Oct 25.
7
Long-term prognostic value of quantitative myocardial perfusion in patients with chest pain and normal coronary arteries.胸痛且冠状动脉正常患者定量心肌灌注的长期预后价值。
J Nucl Cardiol. 2019 Dec;26(6):1844-1852. doi: 10.1007/s12350-018-1448-8. Epub 2018 Oct 4.
8
The performance of non-invasive tests to rule-in and rule-out significant coronary artery stenosis in patients with stable angina: a meta-analysis focused on post-test disease probability.无创性检查在稳定型心绞痛患者中用于明确或排除有意义的冠状动脉狭窄的表现:侧重于检测后疾病概率的荟萃分析。
Eur Heart J. 2018 Sep 14;39(35):3322-3330. doi: 10.1093/eurheartj/ehy267.
9
Hybrid cardiac imaging using PET/MRI: a joint position statement by the European Society of Cardiovascular Radiology (ESCR) and the European Association of Nuclear Medicine (EANM).采用 PET/MRI 的心脏混合成像:欧洲心血管放射学会(ESCR)和欧洲核医学协会(EANM)的联合立场声明。
Eur Radiol. 2018 Oct;28(10):4086-4101. doi: 10.1007/s00330-017-5008-4. Epub 2018 May 2.
10
Motion Correction and Its Impact on Absolute Myocardial Blood Flow Measures with PET.运动校正及其对 PET 绝对心肌血流测量的影响。
Curr Cardiol Rep. 2018 Mar 24;20(5):34. doi: 10.1007/s11886-018-0977-8.