Nuclear Medicine Unit, Department of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, Largo Brambilla 3, 50134, Florence, Italy.
Radiology & Molecular Imaging, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.
Eur J Nucl Med Mol Imaging. 2021 Apr;48(4):1040-1069. doi: 10.1007/s00259-020-05046-9. Epub 2020 Nov 2.
The use of cardiac PET, and in particular of quantitative myocardial perfusion PET, has been growing during the last years, because scanners are becoming widely available and because several studies have convincingly demonstrated the advantages of this imaging approach. Therefore, there is a need of determining the procedural modalities for performing high-quality studies and obtaining from this demanding technique the most in terms of both measurement reliability and clinical data. Although the field is rapidly evolving, with progresses in hardware and software, and the near perspective of new tracers, the EANM Cardiovascular Committee found it reasonable and useful to expose in an updated text the state of the art of quantitative myocardial perfusion PET, in order to establish an effective use of this modality and to help implementing it on a wider basis. Together with the many steps necessary for the correct execution of quantitative measurements, the importance of a multiparametric approach and of a comprehensive and clinically useful report have been stressed.
在过去几年中,心脏 PET 的使用,特别是定量心肌灌注 PET 的使用一直在增加,因为扫描仪越来越普及,而且多项研究令人信服地证明了这种成像方法的优势。因此,需要确定进行高质量研究的程序模式,并从这项高要求的技术中获得尽可能多的测量可靠性和临床数据。尽管该领域发展迅速,硬件和软件都在不断进步,而且新示踪剂的前景也近在咫尺,但 EANM 心血管委员会认为,以更新的文本展示定量心肌灌注 PET 的最新技术状态是合理且有用的,以便有效利用这种方式,并帮助更广泛地实施这种方式。除了正确执行定量测量所需的许多步骤外,还强调了多参数方法和全面、具有临床意义的报告的重要性。