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Causation of type 2 diabetes -- the Gordian knot unravels.

作者信息

Taylor Roy

机构信息

University of Newcastle upon Tyne Medical School, Newcastle upon Tyne, United Kingdom.

出版信息

N Engl J Med. 2004 Feb 12;350(7):639-41. doi: 10.1056/NEJMp038239.

DOI:10.1056/NEJMp038239
PMID:14960738
Abstract
摘要

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Causation of type 2 diabetes -- the Gordian knot unravels.2型糖尿病的病因——难解之结被解开。
N Engl J Med. 2004 Feb 12;350(7):639-41. doi: 10.1056/NEJMp038239.
2
Troglitazone effects on gene expression in human skeletal muscle of type II diabetes involve up-regulation of peroxisome proliferator-activated receptor-gamma.曲格列酮对II型糖尿病患者骨骼肌基因表达的影响涉及过氧化物酶体增殖物激活受体γ的上调。
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Treatment of insulin resistance with peroxisome proliferator-activated receptor gamma agonists.过氧化物酶体增殖物激活受体γ激动剂治疗胰岛素抵抗
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Effects of troglitazone on cellular differentiation, insulin signaling, and glucose metabolism in cultured human skeletal muscle cells.曲格列酮对培养的人骨骼肌细胞中细胞分化、胰岛素信号传导及葡萄糖代谢的影响。
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New perspectives into the molecular pathogenesis and treatment of type 2 diabetes.2型糖尿病分子发病机制与治疗的新视角
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Improved skeletal muscle oxidative enzyme activity and restoration of PGC-1 alpha and PPAR beta/delta gene expression upon rosiglitazone treatment in obese patients with type 2 diabetes mellitus.罗格列酮治疗肥胖2型糖尿病患者后骨骼肌氧化酶活性增强，PGC-1α和PPARβ/δ基因表达恢复。
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Thiazolidinediones.噻唑烷二酮类
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Skeletal muscle peroxisome proliferator- activated receptor-gamma expression in obesity and non- insulin-dependent diabetes mellitus.肥胖症和非胰岛素依赖型糖尿病中骨骼肌过氧化物酶体增殖物激活受体γ的表达
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