Fergie N, Bayston R, Pearson J P, Birchall J P
Department of Otolaryngology and Head and Neck Surgery, Queen's Medical Centre, Nottingham, UK.
Clin Otolaryngol Allied Sci. 2004 Feb;29(1):38-46. doi: 10.1111/j.1365-2273.2004.00767.x.
Recent attention has focused on the possibility that otitis media with effusion (OME) may represent a chronic infective state such as those evidenced in conditions secondary to biofilms or small colony variants. This review discusses the evidence suggesting that this may indeed be the case and explains why this may prove to be important in the future management of this condition by discussing recent advances in understanding these bacterial phenotypic variants.
近期的关注焦点在于，分泌性中耳炎（OME）可能代表一种慢性感染状态，比如在生物膜或小菌落变异体引发的病症中所证实的那样。本综述讨论了表明情况确实如此的证据，并通过探讨在理解这些细菌表型变异体方面的最新进展，解释了为何这可能在该病症未来的治疗中被证明至关重要。
