Oh Byeong Cheol, Lim Young-Min, Kwon Young Mee, Khang Shin Kwang, Kim Kwang Kuk
Department of Neurology, University of Ulsan College of Medicine, Asan Medical Center, 388-1 Pungnap-dong, Songpa-gu, Seoul 138-736, Korea.
J Korean Med Sci. 2004 Feb;19(1):130-3. doi: 10.3346/jkms.2004.19.1.130.
Peripheral neuropathies occur in lymphoma patients. Causes of neuropathy include chemotherapy, opportunistic infections, and the lymphoma itself. We report a patient with lymphoma whose chief complaint was a sensory loss in the hands and feet. Electrophysiologic studies and sural nerve biopsy showed sensory polyneuropathies. We hypothesize that this neuropathy is associated with lymphoma-related ganglionopathy, and among the possible causes, we suspect that a systemic cause such as a paraneoplastic syndrome is the most likely pathogenic etiology. However, further follow-up will be necessary to see whether sensory symptoms change with lymphoma treatment.
外周神经病变发生于淋巴瘤患者。神经病变的原因包括化疗、机会性感染以及淋巴瘤本身。我们报告了一名淋巴瘤患者，其主要症状为手足感觉丧失。电生理研究和腓肠神经活检显示为感觉性多发性神经病变。我们推测这种神经病变与淋巴瘤相关的神经节病有关，在可能的病因中，我们怀疑系统性病因如副肿瘤综合征是最可能的致病原因。然而，需要进一步随访以观察感觉症状是否随淋巴瘤治疗而改变。
