Parajón Teresa, Lupón Josep, González Beatriz, Urrutia Agustín, Altimir Salvador, Coll Ramón, Prats Montserrat, Valle Vicente
Unitat d'Insuficiència Cardíaca, Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona, España.
Rev Esp Cardiol. 2004 Feb;57(2):155-60.
Quality of life is an important end-point in heart failure studies, as well as mortality and hospitalization rates. The Minnesota Living With Heart Failure Questionnaire is the instrument used most widely to evaluate quality of life in research studies. We used this questionnaire to evaluate quality of life in a general population attended by a heart failure unit in Spain.
326 patients seen for the first time at the unit were evaluated. We analyzed the relationship between the questionnaire score and different clinical and demographic factors.
The median global score on the Minnesota Living With Heart Failure Questionnaire was relatively low (28). We found a strong correlation (P<.001) between the score and functional class, sex (women had higher scores), and diabetes. We also found a correlation between the score and number of hospital admissions in the previous year (P<.001), anemia (P<.001) and etiology (P=.01), and a weak trend toward higher scores with increasing age (P=.04). The highest scores were observed in patients with valve disease disorders (43), and the lowest were seen in patients with alcoholic cardiomyopathy (20) and ischemic heart disease (24). We found no correlation with time of evolution of heart failure or with left ventricular ejection fraction.
The scores on the Minnesota Living With Heart Failure Questionnaire in a general population attended by a heart failure unit in Spain were relatively low. However, we found a strong correlation between this score and functional class, and also between this score and number of admissions in the previous year. These results suggest that the questionnaire adequately reflects the severity of the disease.
生活质量是心力衰竭研究中的一个重要终点指标,死亡率和住院率也是如此。明尼苏达心力衰竭生活问卷是研究中最广泛用于评估生活质量的工具。我们使用该问卷对西班牙一家心力衰竭科诊治的普通人群的生活质量进行评估。
对首次到该科室就诊的326例患者进行评估。我们分析了问卷得分与不同临床及人口统计学因素之间的关系。
明尼苏达心力衰竭生活问卷的全球得分中位数相对较低(28分)。我们发现得分与心功能分级、性别(女性得分更高)及糖尿病之间存在强相关性(P<0.001)。我们还发现得分与前一年的住院次数(P<0.001)、贫血(P<0.001)及病因(P=0.01)之间存在相关性,且随着年龄增长得分有升高的微弱趋势(P=0.04)。瓣膜病患者得分最高(43分),酒精性心肌病患者(20分)和缺血性心脏病患者(24分)得分最低。我们未发现得分与心力衰竭病程或左心室射血分数之间存在相关性。
西班牙一家心力衰竭科诊治的普通人群的明尼苏达心力衰竭生活问卷得分相对较低。然而,我们发现该得分与心功能分级之间存在强相关性,且与前一年的住院次数之间也存在相关性。这些结果表明该问卷能充分反映疾病的严重程度。