Glyprolines and semax prevent stress-induced microcirculatory disturbances in the mesentery.
作者信息
Kopylova G N, Smirnova E A, Sanzhieva L Ts, Umarova B A, Lelekova T V, Samonina G E
机构信息
Department of Human and Animal Physiology, Biological Faculty, M. V. Lomonosov Moscow State University, Russia.
出版信息
Bull Exp Biol Med. 2003 Nov;136(5):441-3. doi: 10.1023/b:bebm.0000017087.90585.a9.
Abstract
One-hour immobilization stress considerably disturbed microcirculation in the mesentery: blood flow in small mesenteric vessels decreased or stopped and numerous hemorrhages appeared. Lymphatic vessels lost spontaneous activity and did not respond to norepinephrine. Administration of Semax and glyprolines 1 h before stress decreased the severity of stress-induced microcirculatory disturbances. PGP and GP were most effective in this respect.
摘要
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