Strand Trond-Eirik, Malayeri Columbo, Eskonsipo Petri K J, Grimsrud Tom K, Norstein Jarle, Grotmol Tom
Faculty of Medicine, University of Tromsø, N-9037 Tromsø, Norway.
Cancer Causes Control. 2004 Feb;15(1):27-33. doi: 10.1023/B:CACO.0000016575.31651.b0.
To describe the national trends in lung cancer incidence among young adults and the relationship to adolescent smoking.
Between 1954 and 1998, a total of 1108 non-carcinoid lung cancers were reported to the Cancer Registry of Norway in individuals aged 20-44 years. Temporal variations were studied in age and sex specific rates, in age-adjusted rates, and by means of age-period-cohort modelling. The association between cancer incidence and smoking prevalence was evaluated.
The lung cancer incidence rate among women aged 40-44 in Norway continued to increase into the most recent time interval (1994-1998) whereas the rate among men aged 40-44 was essentially constant after 1970. Consequently, lung cancer incidence rates converged among male and female young adults. Lung cancer incidence rates at age 40-44 were highly correlated with smoking prevalence at age 15-19 in males ( r = 0.88) and females ( r = 0.82) within the same birth cohort.
The lung cancer incidence rate in young Norwegian women now equals that of men. The risk at age 40-44 was closely associated with teenage smoking, indicating that duration and age of onset are important.
描述年轻成年人肺癌发病率的全国趋势及其与青少年吸烟的关系。
1954年至1998年间，挪威癌症登记处共报告了1108例20 - 44岁非类癌性肺癌病例。研究了年龄和性别特异性发病率、年龄调整发病率的时间变化，并采用年龄-时期-队列模型进行分析。评估了癌症发病率与吸烟流行率之间的关联。
挪威40 - 44岁女性的肺癌发病率在最近时间段（1994 - 1998年）持续上升，而40 - 44岁男性的发病率在1970年后基本保持稳定。因此，年轻成年男性和女性的肺癌发病率趋于一致。在同一年龄队列中，40 - 44岁的肺癌发病率与15 - 19岁男性（r = 0.88）和女性（r = 0.82）的吸烟流行率高度相关。
挪威年轻女性的肺癌发病率现已与男性相当。40 - 44岁的风险与青少年吸烟密切相关，表明吸烟持续时间和开始吸烟年龄很重要。
