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A ratiometric fluorescent probe for imaging hydroxyl radicals in living cells.

作者信息

Soh Nobuaki, Makihara Koji, Sakoda Emino, Imato Toshihiko

机构信息

Department of Applied Chemistry, Graduate School of Engineering, Kyushu University, 6-10-1, Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan.

出版信息

Chem Commun (Camb). 2004 Mar 7(5):496-7. doi: 10.1039/b314204c. Epub 2004 Feb 2.

Abstract

A novel fluorescent probe, the detection mechanism of which is based on the 'on-off' switching of a FRET triggered by the *OH-induced cleavage of a DNA strand, has been developed for the ratiometric imaging of *OH.

摘要

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